Asbestos-related diseases include cancers such as mesothelioma, lung cancer, ovarian cancer and laryngeal cancer. They also include non-malignant diseases such as asbestosis and pleural plaques. Any amount of asbestos exposure can cause asbestos-related cancer.
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Asbestos is linked to several diseases, both benign (non-cancerous) and malignant (cancerous). Asbestos exposure can cause mesothelioma and lung cancer as well as non-malignant lung diseases such as asbestosis, pleural plaques and pleural thickening. Malignancies with possible asbestos links include bile duct cancer, colon cancer, pharyngeal cancer and stomach cancer.
Cancers Linked to Asbestos Exposure
Laryngeal cancer
Lung cancer
Mesothelioma (pleural, peritoneal, and pericardial)
Ovarian cancer
Benign Asbestos-Related Diseases
Asbestosis
Collapsed lung
COPD
Pericardial effusion
Peritoneal effusion (ascites)
Pleural effusion
Pleural plaques
Pleural thickening
Pleuritis (pleurisy)
Any amount of asbestos exposure can lead to disease. Because many asbestos-related diseases have a long latency period, it can take years before symptoms occur. Even if a disease is benign, it can still become life-threatening if left untreated.
Summary
Asbestos exposure can cause various cancers and non-malignant lung diseases. Asbestos-related cancers include mesothelioma, lung cancer, larynx cancer and ovarian cancer. Exposure to asbestos can also lead to asbestosis, pleural plaques, pleural thickening and benign pleural effusions. Patients can be diagnosed with one or more asbestos-related diseases at a time.
Malignant Asbestos-Related Diseases
Malignant asbestos-related diseases include mesothelioma, lung cancer, ovarian cancer and laryngeal cancer. Evidence is growing for bile duct cancer. Asbestos exposure causes these diseases and can also cause other health problems, such as asbestosis and pleural plaques.
Any amount of exposure can cause asbestos-related cancer. People with the highest risk have inhaled or ingested large amounts of asbestos for extended periods of time.
Mesothelioma
Mesothelioma forms in the membranes covering body cavities. Tumors can appear on the lining of the lungs, stomach, heart or testes. Chest or abdominal pain and shortness of breath affect many patients.
Ovarian Cancer
Ovarian cancer forms in a woman’s ovaries, the reproductive organs that make and release eggs. A 2023 systematic review found that asbestos exposure in women increased the risk of death due to ovarian cancer.
Laryngeal Cancer
Laryngeal cancer develops in the larynx or “voice box.” A recent study of occupational risk factors for laryngeal cancer found that workers exposed to asbestos are 3.68 times as likely to develop this disease.
Lung Cancer
Asbestos exposure can cause both small cell and non-small cell lung cancer. Inhaled asbestos fibers can change specific genes in the body, eventually developing into asbestos-lung cancer over the course of 15 to 35 years.
Other Asbestos-Related Cancers
Asbestos exposure is a risk factor for bile duct and cancer in people without any other known risk factors. Other cancers possibly associated with asbestos exposure include esophageal cancer, gallbladder cancer, kidney cancer and throat cancer. Studies on asbestos and these cancers are inconsistent.
Malignant and benign diseases could potentially develop after one exposure. However, malignant conditions usually result from years of cumulative exposure.
People at the highest risk of developing malignant asbestos-related diseases are those who work in construction and other professions using asbestos-containing materials. These individuals may be eligible for cancer screenings because of their long-term asbestos exposure.
Kevin Hession
Verified Asbestos.com Survivor
Pleural Mesothelioma Survivor First Experienced 4 Cases of Pleurisy
Kevin Hession had shortness of breath and chest pain. In total, he experienced 4 cases of pleurisy, which causes inflammation of tissue that lines the lungs and chest cavity. Following case No. 4, Kevin underwent exploratory surgery. Tests came back negative for cancer, but he underwent 4 chemotherapy infusions and then decortication surgery. The surgeon found mesothelioma cells.
Benign Asbestos-Related Diseases
Benign asbestos-related diseases, such as asbestosis and pleural effusions, aren’t cancerous. These are somewhat more common than asbestos-related malignancies.
Even though these diseases are benign, they have the potential to become dangerous. Talk to your doctor if you begin experiencing symptoms of an asbestos-related disease, especially if you have previously been exposed to asbestos.
Asbestosis
Asbestosis is a chronic lung disease caused by exposure to asbestos fibers, leading to scarring and inflammation. Asbestosis is prevalent in insulating, shipyard work, pipefitting and asbestos manufacturing.
Pleural Effusions
Pleural effusions are a fluid buildup between pleural membrane layers, leading to shortness of breath. Effusions are often a symptom of late-stage mesothelioma or nonmesothelioma cancers.
Peritoneal Effusions
Peritoneal effusion (ascites) refers to excess fluid in the abdominal cavity. Peritoneal mesothelioma is a rare cause. Effusions are more likely linked to benign conditions or other types of cancer.
Pericardial Effusions
Pericardial effusion is the collection of excess fluid between the membrane layers surrounding the heart (pericardium). It may be a sign of malignant asbestos disease such as pericardial mesothelioma.
Pleural Plaques
Pleural plaques are hardened calcium deposits that form on the pleura after asbestos exposure. These plaques are not considered a serious health issue, but they can make breathing painful if they are too thick.
Pleuritis
Pleuritis, also known as pleurisy, is inflammation of the pleura. Asbestos exposure creates inflamed surfaces that become rough and rub together, resulting in sharp chest or shoulder pain. Pleurisy may occur with pleural effusions.
Diffuse Pleural Thickening
Asbestos exposure can cause diffuse pleural thickening. The condition affects 8 centimeters to one-quarter of the pleura. Diffuse pleural thickening may decrease lung function, but it rarely leads to death.
Collapsed Lung
A collapsed lung is an uncommon asbestos-related condition. It can develop when air becomes trapped in the pleural space. The collapse may be partial (rounded atelectasis) or total (pneumothorax).
COPD
Asbestos exposure does not directly cause chronic obstructive pulmonary disease (COPD), but it can raise the risk. COPD may weaken the lungs, making people more susceptible to other asbestos-related diseases.
Many benign asbestos-related diseases are signs of malignant mesothelioma. However, they may also point to noncancerous health problems such as viral infections or lung injury.
Your doctor will run a series of tests to determine what is causing your symptoms. Proper treatment of benign asbestos-related diseases prevents further complications later on.
When inhaled, asbestos fibers can become trapped in the lung tissue or mesothelium, the thin lining of the body’s cavities. They may also travel through the bloodstream and become stuck in the mesothelium lining other organs, such as the abdominal cavity or heart.
Patients inhale asbestos, which causes chronic inflammation. Those inflammatory changes lead to genetic changes in a cell, changing its DNA to a cancer cell.
Many asbestos-related diseases have a long latency period and take several years to develop. It’s important to discuss any asbestos exposure with your doctor so they can monitor your health over time. Early screening and detection are key to diagnosing and treating asbestos-related diseases.
19,000
Number of people in the U.S. exposed to asbestos who The Mesothelioma Center at Asbestos.com has helped since 2017.
Commonly Asked Questions About Asbestos-Related Diseases
What are the 4 major asbestos-related diseases?
Several diseases may develop following asbestos exposure. These may be malignant or benign. There are 4 types of cancer caused by asbestos:
Laryngeal cancer
Lung cancer
Mesothelioma
Ovarian cancer
Evidence suggests asbestos may cause gastrointestinal tumors, including bile duct cancer. Benign conditions include asbestosis, pleural effusion, pleural thickening and pleural plaques.
How many years does it take for asbestos-related diseases to develop?
Asbestos-related diseases are often latent, meaning they take several years to develop. According to the National Cancer Institute, it may take 20 to 60 years for symptoms of asbestos-related diseases to show.
What if I’ve been exposed to asbestos?
If you have been exposed to asbestos, it is important to speak with your doctor. They will perform screening tests to identify lung damage and diagnose asbestos-related diseases.
The sources on all content featured in The Mesothelioma Center at Asbestos.com include medical and scientific studies, peer-reviewed studies and other research documents from reputable organizations.
Mizuhashi, K. et al. (2024, February 10). Detailed clinical course of a patient with rapidly progressing sarcomatoid pleural mesothelioma without p16 deletion with systemic haematogenous metastasis to soft tissues. Retrieved from: https://casereports.bmj.com/content/17/2/e257618.info
Seyyedsalehi, M., Boffetta P. (2024, February 10). Occupational asbestos exposure and risk of esophageal cancer: a systematic review and meta-analysis. Retrieved from: https://onlinelibrary.wiley.com/doi/10.1002/ijc.34881
Visonà, S., et al. (2023, December 9). Asbestos burden in lungs of mesothelioma patients with pleural plaques, lung fibrosis and/or ferruginous bodies at histology: a postmortem SEM-EDS study. Retrieved from: https://academic.oup.com/carcin/article/45/3/131/7464959?login=false
Miller, A. (2023, November 29). Recognizing the pleura in asbestos-related pleuropulmonary disease: known and new manifestations of pleural fibrosis. Retrieved from: https://onlinelibrary.wiley.com/doi/10.1002/ajim.23553
Wang, D., Wang, Y., Chu, S. (2023, November 20). Case report: early diagnosis and bevacizumab-based chemotherapy for primary pericardial mesothelioma: a case with occupational asbestos exposure history. Retrieved from: https://www.frontiersin.org/articles/10.3389/fcvm.2023.1257373/full
Vasuri, F., et al. (2023, February 13). Asbestos exposure as an additional risk factor for small duct intrahepatic cholangiocarcinoma: a pilot study. Retrieved from: https://www.nature.com/articles/s41598-023-27791-1
Brims, F., et al. (2022, December 29). Correlation of lung function with ultra-low-dose CT-detected lung parenchymal abnormalities: a cohort study of 1344 asbestos exposed individuals. Retrieved from: https://bmjopenrespres.bmj.com/content/9/1/e001366.info
Ringen, K., et al. (2022, November 17). How much have adverse occupational health outcomes among construction workers improved over time? Evidence from 25 years of medical screening. Retrieved https://onlinelibrary.wiley.com/doi/10.1002/ajim.23445
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Dixon, S. (2024, August 9). Asbestos-Related Diseases. Asbestos.com. Retrieved November 20, 2024, from https://www.asbestos.com/mesothelioma/related-diseases/
MLA
Dixon, Suzanne. "Asbestos-Related Diseases." Asbestos.com, 9 Aug 2024, https://www.asbestos.com/mesothelioma/related-diseases/.
Chicago
Dixon, Suzanne. "Asbestos-Related Diseases." Asbestos.com. Last modified August 9, 2024. https://www.asbestos.com/mesothelioma/related-diseases/.
A medical doctor who specializes in mesothelioma or cancer treatment reviewed the content on this page to ensure it meets current medical standards and accuracy.
Please read our editorial guidelines to learn more about our content creation and review process.
Dr. Jacques Fontaine is a thoracic surgeon at Moffitt Cancer Center in Tampa, Florida, where he heads up the Mesothelioma Research and Treatment Center. He specializes in minimally invasive robotic surgery and aggressive surgeries for mesothelioma.
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